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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
20
Human Site:
S2145
Identified Species:
44
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
S2145
L
S
E
S
S
I
P
S
V
S
D
T
S
T
P
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
Q2570
S
S
S
S
S
E
K
Q
R
F
Y
S
C
D
R
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2142
L
S
E
S
S
I
P
S
V
S
D
T
S
T
P
Dog
Lupus familis
XP_547425
2465
277756
S2287
L
S
E
S
S
I
P
S
I
S
D
T
S
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
S2105
L
S
E
S
S
I
P
S
I
S
D
T
S
T
P
Rat
Rattus norvegicus
Q07652
2222
252098
S2054
L
S
E
S
S
I
P
S
I
S
D
T
S
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
T2027
R
D
H
T
P
Y
Y
T
P
L
I
Q
V
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
K1670
M
K
E
S
I
E
A
K
F
I
M
N
N
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
L1692
R
A
G
I
G
R
R
L
P
P
T
P
S
K
P
Honey Bee
Apis mellifera
NP_001159376
1904
215872
D1745
P
S
P
I
H
H
I
D
R
G
R
H
Y
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
S1807
M
D
P
E
S
S
Q
S
S
P
P
S
R
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
13.3
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
26.6
N.A.
20
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
19
0
0
0
0
0
10
0
0
46
0
0
19
0
% D
% Glu:
0
0
55
10
0
19
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
10
0
10
10
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
19
10
46
10
0
28
10
10
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
10
0
0
0
0
0
19
0
% K
% Leu:
46
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% L
% Met:
19
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
10
0
19
0
10
0
46
0
19
19
10
10
0
10
55
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% Q
% Arg:
19
0
0
0
0
10
10
0
19
0
10
0
10
0
19
% R
% Ser:
10
64
10
64
64
10
0
55
10
46
0
19
55
0
0
% S
% Thr:
0
0
0
10
0
0
0
10
0
0
10
46
0
46
19
% T
% Val:
0
0
0
0
0
0
0
0
19
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _